H.V. Desai Senior College of Arts Science and Commerce is a college in Pune. It is affiliated to University of Pune. It is run by Poona Gujarathi Kelvani Mandal. It was established in 1984 by Padmabhushan Dr.Karmaveer Bhaurao Patil.

Courses offered in H.V. Desai Senior College of Arts Science and Commerce: B.A., B.Com., B.B.A., B.C.A.,  B.Sc.-Computer Science,  M.Com. M.Sc-Computer Science Diploma in Communication & Journalism