Asthenia, or de-sthenia (lack of strength, vigor) and has a weakening of the body, physical fatigue. By extension, it can affect the mental state, the libido and the intellect.
The fatigue is a symptom and a cause for medical consultation very common: In general medicine, 50% of patients complain of fatigue. The issue of consultation is to differentiate between a general fatigue, often a reaction to stress, chronic physical or mental (which can be closer to fatigue, but sometimes secondary to systemic disease) and real alarm signal of a specific pathophysiological process.
Asthenic type 'general fatigue'
- Stress Chronic;
- neurosis (chronic anxiety in particular);
- chronic fatigue syndrome (sequelae of mononucleosis);
- Reactions to certain drugs.
Asthenia revealing in the context of a specific condition:
- Iron deficiency (anemia due to iron deficiency);
- certain viral infections: influenza, mononucleosis, HIV (primary infection), hepatitis B and C (the only symptom of HCV), rhinitis, chronic;
- certain bacterial infections: brucellosis, Q fever, Lyme disease, tuberculosis;
- parasitic infections such trypanosomiasis (sleeping sickness);
- Endocrine disorders: hypothyroidism, Addison's disease, Cushing syndrome, hypopituitarism, pituitary adenoma;
- Genetic diseases especially the hemochromatosis gene (hyperabsorption iron);
- nutritional deficiency or poorly absorbing vitamin B9 (folic acid);
- myasthenia gravis;
- Reaching the spinal cord;
- asthenia iatrogenic: abuse of sedatives (medicines hypnotics), benzodiazepines, certain antipsychotics;
- substance abuse: marijuana, alcohol, heroin, morphine and its derivatives;
- Food poisoning due to consumption of mushrooms poisonous;
- acute radiation above 2 Gy;
- Disease in Philadelphia chromosome (1 or 2 cases per 100 000 people).
Causes of asthenia
- Addison's disease
- Chronic fatigue syndrome
- Chronic pain
- deconditioning/sedentary lifestyle
- Dehydration and electrolyte disturbance
- Depression and PMDD
- Heart disease
- Medications including amiodarone, Anastrazole, and fentanyl
- Paraneoplastic syndrome
- Polymyalgia Rheumatica
- Pulmonary disease
- Renal disease
- Sleep disorders
- Temporal arteritis